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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR2B
All Species:
41.52
Human Site:
T235
Identified Species:
60.89
UniProt:
P31323
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31323
NP_002727.2
418
46302
T235
Y
N
T
P
R
A
A
T
I
T
A
T
S
P
G
Chimpanzee
Pan troglodytes
XP_001148361
477
52826
T294
Y
N
T
P
R
A
A
T
I
T
A
T
S
P
G
Rhesus Macaque
Macaca mulatta
XP_001089109
461
51060
T278
Y
N
T
P
R
A
A
T
I
T
A
T
S
P
G
Dog
Lupus familis
XP_849179
417
46163
T234
Y
N
T
P
R
A
A
T
I
T
A
T
S
P
G
Cat
Felis silvestris
Mouse
Mus musculus
P31324
416
46149
T233
Y
N
T
P
R
A
A
T
I
T
A
T
S
P
G
Rat
Rattus norvegicus
P12369
416
46104
T233
Y
N
T
P
R
A
A
T
I
T
A
T
S
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509189
323
36258
R154
G
A
L
W
G
L
D
R
V
T
F
R
R
I
I
Chicken
Gallus gallus
Q5ZM91
382
43332
T210
E
L
A
L
I
Y
G
T
P
R
A
A
T
V
K
Frog
Xenopus laevis
NP_001084637
402
45172
T219
Y
N
T
P
R
A
A
T
I
V
A
T
S
V
G
Zebra Danio
Brachydanio rerio
NP_001070838
397
44672
T217
Y
N
T
P
R
A
A
T
I
I
A
K
D
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P81900
377
42730
T201
Y
N
M
P
R
A
A
T
V
Q
A
E
T
S
G
Honey Bee
Apis mellifera
XP_392905
383
43849
T207
Y
N
M
P
R
A
A
T
I
K
A
I
T
N
G
Nematode Worm
Caenorhab. elegans
P30625
366
41449
A197
L
I
Y
G
T
P
R
A
A
T
V
I
A
K
T
Sea Urchin
Strong. purpuratus
Q26619
369
41770
T198
Y
N
T
P
R
A
A
T
I
A
A
T
T
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
K237
D
F
Y
V
N
D
N
K
V
N
S
S
G
P
G
Red Bread Mold
Neurospora crassa
Q01386
385
42138
M211
S
F
G
E
L
A
L
M
Y
N
A
P
R
A
A
Conservation
Percent
Protein Identity:
100
86.5
90
96.6
N.A.
97.1
96.8
N.A.
70.3
34.6
78.4
68.1
N.A.
44
47.6
31.8
50.9
Protein Similarity:
100
87.2
90.2
98
N.A.
98
98.5
N.A.
74.1
52.3
85.4
80.6
N.A.
64.1
63.8
50.9
66.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
13.3
86.6
73.3
N.A.
60
66.6
6.6
80
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
20
86.6
73.3
N.A.
73.3
73.3
13.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.9
36.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.9
51.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
75
69
7
7
7
82
7
7
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
7
7
0
0
0
0
0
7
7
0
% D
% Glu:
7
0
0
7
0
0
0
0
0
0
0
7
0
7
0
% E
% Phe:
0
13
0
0
0
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
7
0
7
7
7
0
7
0
0
0
0
0
7
0
75
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
7
0
0
0
63
7
0
13
0
7
7
% I
% Lys:
0
0
0
0
0
0
0
7
0
7
0
7
0
7
7
% K
% Leu:
7
7
7
7
7
7
7
0
0
0
0
0
0
0
0
% L
% Met:
0
0
13
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
69
0
0
7
0
7
0
0
13
0
0
0
7
0
% N
% Pro:
0
0
0
69
0
7
0
0
7
0
0
7
0
44
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Q
% Arg:
0
0
0
0
69
0
7
7
0
7
0
7
13
0
0
% R
% Ser:
7
0
0
0
0
0
0
0
0
0
7
7
44
7
0
% S
% Thr:
0
0
57
0
7
0
0
75
0
50
0
50
25
0
7
% T
% Val:
0
0
0
7
0
0
0
0
19
7
7
0
0
13
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
69
0
13
0
0
7
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _